Due to the existence of gas⁃liquid⁃solid three⁃phase and the installation of internal components, the transfer and reaction process of slurry bed reactor in Fischer⁃Tropsch synthesis is complex, which poses great challenges in reactor design and industrial scale⁃up. This paper introduced the structure of slurry bubble column reactor and also reviewed the recent researches on dynamics and reactor scale⁃ups. The influences of internals on hydrodynamics and scale⁃up were analyzed as well. Crucial factors in terms of structure and model in the process of reactor design were included, which may provide a feasible scheme and solution for optimization and scale⁃up of slurry bubble column reactor.